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Will Dark Chocolate a Day Keep the Doctor Away?

may additionally 31, 2012 -- have to humans at excessive hazard of coronary heart assault and stroke eat dark chocolate every day?

maybe, in line with a brand new study from Australia.

"dark chocolate can be a pleasing and effective way of turning in essential dietary additives that can offer fitness blessings to the ever growing numbers of human beings at improved threat of cardiovascular ailment," says researcher Christopher M. Reid, PhD, professor of cardiovascular epidemiology and preventive medication at Monash university in Australia.

Reid and his group built a mathematical model to are expecting the long-term health consequences of ingesting dark chocolate day by day in high-risk people. They did no longer observe actual people ingesting actual chocolate.

The researchers also computed whether or not it'd be fee-powerful to spend money on a public schooling marketing campaign approximately dark chocolate's benefits. They observed it might be.

numerous studies h…

Why Eating Less Red Meat May Help Your Heart

Nov. 7, 2014 -- Saturated fat in red meat has long been linked to heart disease. But new research suggests it might not be the only culprit.

Bacteria in the intestines convert carnitine, a protein building block that's especially plentiful in beef, lamb, and venison, into compounds that speed up hardening and thickening of artery walls, according to a new study.

Generally, the redder the meat, the more carnitine it has. Although pork is considered a red meat, it doesn't have as much carnitine as beef, lamb and venison, and chicken and fish have even less.

Scientists behind the study, published in the journal Cell Metabolism, say their work suggests new targets for drugs to prevent and treat heart disease. And, they say, it raises concerns about the safety of dietary supplements that contain carnitine and a related compound.

The name “carnitine” comes from the Latin word for “meat” or “flesh.” It’s not considered an essential nutrient in food, because “we make all the carnitine we need on our own,” says study researcher Stanley Hazen, MD, PhD, of the Miller Family Heart and Vascular Institute at Cleveland Clinic. “Every cell in our body needs that carnitine,” which is essential for converting fats into energy, he says.

Studies have repeatedly shown a strong link between the amount of red meat people eat and their risk of dying of heart disease, Hazen says. But “the amount of cholesterol and fat in the red meat is not enough for the increased risk that’s observed,” he says. “There’s more to it than just the fat.”

The trillions of microorganisms -- mainly bacteria -- that live in the intestines help with nutrition and the immune system. They're as varied as the people they inhabit, due mainly to diet and genetics.

“When we feed ourselves, we’re feeding our microbes, too,” Hazen says. The more carnitine you eat, the more likely you'll have microbes in your gut that will convert it to the compounds that promote hardening and thickening of artery walls, he said.


“The bacteria in our gut serve as a giant bioreactor,” says Jason Goldsmith, MD, PhD. He's a gastroenterology resident and post-doc fellow at the University of Michigan who was not involved in the new research. “They have an effect on us, and we have an effect on them.”

Another Potentially Heart-Breaking Finding

The new study, using mice, found that carnitine from the red meat is converted by gut microbes into a substance known as GBB. Then GBB is converted into compounds called trimethylamine (TMA) and TMAO, also by the gut microbes. All of that increases hardening of the arteries.

But give the mice antibiotics to wipe out their gut bacteria, and the level of GBB in their blood drops to near zero, Hazen’s team found.

“It’s not that the other stuff is not important,” says Andrew Mendelsohn, PhD, referring to other cardiovascular risk factors. “It’s just that this also is important.” Mendelsohn, who was not involved with Hazen’s study, is president and research director of the Regenerative Sciences Institute in Sunnyvale, CA.

Hazen says his new study isn’t about red meat, but about a compound that is more common in red meat than in chicken or fish. "A logical thing would be to cut back eating the nutrient,” he says of carnitine. Although, he says, "We haven’t directly tested yet whether lowering TMAO in humans will lower cardiac risk.”

He was direct about taking dietary supplements containing carnitine or GBB. “Our data should sound an alarm that we need to look at the safety of long-term supplement exposure,” Hazen says.

Hazen and his collaborators last year published the first paper to examine how gut bugs, together with eating red meat, might play a role in raising the risk of plaque buildup in the arteries.

In that study, his team found that supplementing the diet of mice with carnitine changed the types of bacteria in their gut, leading to increased production of trimethylamine, which then converted into TMAO.

The researchers also measured blood levels of carnitine and TMAO in about 2,600 people being checked for heart problems. They found that those numbers predicted heart disease risk better than cholesterol levels.

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Will Dark Chocolate a Day Keep the Doctor Away?

may additionally 31, 2012 -- have to humans at excessive hazard of coronary heart assault and stroke eat dark chocolate every day?

maybe, in line with a brand new study from Australia.

"dark chocolate can be a pleasing and effective way of turning in essential dietary additives that can offer fitness blessings to the ever growing numbers of human beings at improved threat of cardiovascular ailment," says researcher Christopher M. Reid, PhD, professor of cardiovascular epidemiology and preventive medication at Monash university in Australia.

Reid and his group built a mathematical model to are expecting the long-term health consequences of ingesting dark chocolate day by day in high-risk people. They did no longer observe actual people ingesting actual chocolate.

The researchers also computed whether or not it'd be fee-powerful to spend money on a public schooling marketing campaign approximately dark chocolate's benefits. They observed it might be.

numerous studies h…

Higher BPA Levels, More Heart Disease?

Aug. 15, 2012 -- people who have better ranges of the chemical bisphenol A (BPA) in their urine may be more likely to have narrowing in their coronary arteries, a new study indicates.

BPA has been used for extra than forty years in food packaging, metal meals and beverage can liners, and lots of other products. almost all and sundry has detectable levels of BPA, says researcher David Melzer, MD, PhD, professor of epidemiology and public health at England's university of Exeter.

Melzer's new take a look at suggests an affiliation between urinary BPA stages and the width of the coronary arteries, which deliver blood to the coronary heart.

"The people who had narrowed arteries had higher ranges of BPA in their urine," Melzer says.

The look at, published in PLoS One, does not prove that BPA narrowed each person's arteries. Many factors, which includes food regimen and activity, affect coronary heart fitness.

still, Melzer says, "We need to take it severely that …

Millions of Women Unaware They Have Arterial Disease

Feb. 15, 2012 -- among four million and five million girls within the united states have peripheral artery sickness, or PAD, but few are identified and even fewer receive good enough treatment.

In a unique file released at the midpoint of yankee coronary heart Month, the yankee heart affiliation is looking for greater efforts to pick out and diagnose girls at chance for the condition that typically affects the leg arteries, and is likewise calling for extra ladies to be concerned in PAD research.

a chief purpose is to elevate consciousness approximately a disease that tens of millions of women have, but few know approximately, says university of Minnesota clinical faculty professor of drugs, epidemiology, and network fitness, Alan T. Hirsch, MD, who changed into the lead creator of the assertion.

“The fee of dying and the fitness-care prices related to PAD are at the least akin to the ones of heart ailment and stroke,” he says.

PAD raises coronary heart, Stroke danger

Peripheral arter…